Αρθρίτιδα και Κάνναβη

Published by p.arseniou on

  1. https://www.arthritis.org/Documents/Sections/About-Arthritis/arthritis-facts-stats-figures.pdf
  2. http://elire.gr/info_det.php?di=11
  3. Nicola Barrie and Nicholas Manolios. Eur J Rheumatol. 2017 Sep; 4(3): 210–218. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685274/
  4. Gonsiorek W, Lunn C, Fan X, Narula S, Lundell D, Hipkin RW. Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. Mol Pharmacol. 2000;57:1045–50.[PubMed] [Google Scholar]
  5. Sugiura T, Kondo S, Kishimoto S, Miyashita T, Nakane S, Kodaka T, et al. Evidence that 2-arachid-onylglycerol but not N-palmitpylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. J Biol Chem. 2000;275:605–12. https://doi.org/10.1074/jbc.275.1.605. [PubMed] [Google Scholar]
  6. Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F, et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science.
  7. Martin WJ, Patrick SL, Coffin PO, Tsou K, Walker JM. An examination of the central sites of action of cannabinoid-induced antinociception in the rat. Life Sci. 1995;56:2103–9.
  8. Ibrahim MM, Deng H, Zvonok A, Cockayne DA, Kwan J, Mata HP, et al. Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proc Natl Acad Sci U S A. 2003;100:10529–33. https://doi.org/10.1073/pnas.1834309100. [PMC free article] [PubMed] [Google Scholar]
  9. Wotherspoon G, Fox A, McIntyre P, Colley S, Bevan S, Winter J. Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neurosci. 2005;135:235–45. https://doi.org/10.1016/j.neuroscience.2005.06.009. [PubMed] [Google Scholar]
  10. Ibrahim MM, Porreca J, Lai J, Albrecht PJ, Rice FL, Khodorova A, et al. CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proc Natl Acad Sci. 2005;102:3093–98. https://doi.org/10.1073/pnas.0409888102. [PMC free article] [PubMed] [Google Scholar]
  11. McDougall JJ. Arthritis and pain. Neurogenic origin of joint pain. Arthritis Res Ther. 2006;8:220. https://doi.org/10.1186/ar2069. [PMC free article] [PubMed] [Google Scholar]
  12. McDougall JJ. Arthritis and pain. Neurogenic origin of joint pain. Arthritis Res Ther. 2006;8:220. https://doi.org/10.1186/ar2069. [PMC free article] [PubMed] [Google Scholar]
  13. Hunter DJ, McDougall JJ, Keefe FJ. The symptoms of osteoarthritis and the genesis of pain. Med Clin North Am. 2009;93:83–100. https://doi.org/10.1016/j.mcna.2008.08.008. [PubMed] [Google Scholar]
  14. Richardson D, Pearson RG, Kurian N, Latif ML, Garle MJ, Barrett DA, et al. Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther. 2008;10:43–57. https://doi.org/10.1186/ar2401. [PMC free article] [PubMed] [Google Scholar]
  15. Ware MA, Adams H, Guy GW. The medicinal use of cannabis in the UK: results of a nationwide survey. Int J Clin Pract. 2005;59:291–5. https://doi.org/10.1111/j.1742-1241.2004.00271.x. [PubMed] [Google Scholar]
  16. Chiurchi V, Battistini L, Maccarrone M. Endocannabinoid signalling in innate and adaptive immunity. Immunology. 2015;144:352–64. https://doi.org/10.1111/imm.12441. [PMC free article] [PubMed] [Google Scholar]
  17. Maccarrone M, Bab I, Bíró T, Cabral GA, Dey SK, Di Marzo V, et al. Endocannabinoid signaling at the periphery: 50 years after THC. Trends Pharmacol Sci. 2015;36:277–96. https://doi.org/10.1016/j.tips.2015.02.008. [PMC free article] [PubMed] [Google Scholar]
  18. Katchan V, David P, Shoenfeld Y. Cannabinoids and autoimmune diseases: A systematic review. Autoimmunity Rev. 2016;15:513–28. https://doi.org/10.1016/j.autrev.2016.02.008. [PubMed] [Google Scholar]
  19. Kidd BL, Urban LA. Mechanisms of inflammatory pain. Br J Anaesth. 2001;87:3–11. https://doi.org/10.1093/bja/87.1.3. [PubMed] [Google Scholar]
  20. Sancho R, Calzado MA, Di Marzo V, Appendino G, Mu-oz E. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol. 2003;63:429–38. https://doi.org/10.1124/mol.63.2.429. [PubMed] [Google Scholar]
  21. Burstein SH, Zurier RB. Cannabinoids, endocannabinoids, and related analogs in inflammation. AAPS J. 2009;11:109–19. https://doi.org/10.1208/s12248-009-9084-5. [PMC free article] [PubMed] [Google Scholar]
  22. Malfait A, Sumariwalla P, Malik A, Andreakos E, Mechoulam R, Feldmann M. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci. 2000;97:9561–6. https://doi.org/10.1073/pnas.160105897. [PMC free article] [PubMed] [Google Scholar]
  23. Ware MA, Adams H, Guy GW. The medicinal use of cannabis in the UK: results of a nationwide survey. Int J Clin Pract. 2005;59:291–5. https://doi.org/10.1111/j.1742-1241.2004.00271.x. [PubMed] [Google Scholar]
  24. Walker JM, Huang SM. Endocannabinoids in pain modulation. Prostaglandins Leukot Essent Fatty Acids. 2002;66:235–42. https://doi.org/10.1054/plef.2001.0361. [PubMed] [Google Scholar]
  25. Sancho R, Calzado MA, Di Marzo V, Appendino G, Mu-oz E. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol. 2003;63:429–38. https://doi.org/10.1124/mol.63.2.429. [PubMed] [Google Scholar]
  26. Bánvölgyi A, Pozsgai G, Brain SD, Helyes ZS, Szolcsányi J, Ghosh M, et al. Mustard oil induces a transient receptor potential vanilloid 1 receptor-independent neurogenic inflammation and a non-neurogenic cellular inflammatory component in mice. Neuroscience. 2004;125:449–59. https://doi.org/10.1016/j.neuroscience.2004.01.009. [PubMed] [Google Scholar]
  27. Fassold A, Falk W, Anders S, Hirsch T, Mirsky VM, Straub Soluble RH. Neuropilin-2, a nerve repellent receptor, is increased in rheumatoid arthritis synovium and aggravates sympathetic fiber repulsion and arthritis. Arthr Rheum. 2009;60:2892–901. https://doi.org/10.1002/art.24860. [PubMed] [Google Scholar].

Έχετε εγγραφεί επιτυχώς στα ενημερωτικά δελτία The Hemp Way. Χρησιμοποιήστε τον κωδικό THWNR2020 για έκπτωση 10% στην επόμενη αγορά σας.

Συνέβει κάποιο λάθος κατά την αποστολή της αίτησής σας. Παρακαλώ δοκιμάστε ξανά.

Η The Hemp Way θα χρησιμοποιήσει τις πληροφορίες που παρέχετε σε αυτήν την φόρμα για να έρθει σε επαφή μαζί σας και να σας παρέχει νέα και προσφορές προϊόντων.